Rejuran is an innovative skin treatment originating in South Korea. It focuses on skin repair and improvement at the cellular level. The treatment contains polynucleotides (PN) derived from purified salmon DNA. These substances stimulate the skin’s natural regeneration process.
Rejuran does not add volume like a filler, but rather works by improving the quality and structure of the skin. This makes the skin stronger, healthier, and visibly smoother.
The result is smoother skin, improved elasticity, and a natural glow.
Polynucleotides are small DNA fragments that help the skin with cell repair and regeneration. When injected into the skin, they stimulate, among other things:
In addition, polynucleotides have anti-inflammatory and antioxidant properties, which help the skin better withstand external influences.
The polynucleotides in Rejuran are derived from salmon DNA. Although this DNA is not identical to human DNA, its structure is similar, and its high purity and biocompatibility make it highly suitable for medical and cosmetic applications. In addition, the salmon DNA undergoes extensive purification and filtration, ensuring that only the active polynucleotides remain.
The term “salmon sperm” is sometimes used in the media or on social media as a simplified or attention-grabbing description. Historically, polynucleotides were extracted from salmon sperm because it contains a very high concentration of DNA and is relatively easy to isolate.
Today, manufacturers use various sources of salmon tissue from which DNA can be extracted. The DNA is then highly purified and processed into polynucleotides, so that only the active DNA fragments remain. The final product therefore consists of highly purified polynucleotides derived from salmon DNA and no longer contains sperm cells or biological tissue.
Rejuran is ideal for people who want to improve their skin quality naturally and without adding volume.
The treatment is often used for:

First, the skin is numbed with an anesthetic cream. Next, the polynucleotides are injected superficially into the skin using small injections. These stimulate the skin’s natural healing process and improve its quality from within.
There are generally two treatment areas: full face (cheeks, around the mouth, and forehead) or around the eyes. Of course, both treatment areas can be combined.
The first improvements in skin quality and radiance usually become visible after 2 to 4 weeks, after which the skin continues to improve. For optimal results, we recommend 3 treatments with approximately 3 weeks between each session. After that, an annual maintenance treatment is recommended.
After the treatment, small bumps may be visible on the skin for 1–3 days. You may also experience mild redness and/or swelling during this time. This is completely normal and will go away on its own.
Rejuran is ideal for people who want to improve their skin in a subtle and natural way. Because the treatment does not add volume but focuses on skin improvement and repair, the results remain very natural and refined.
In recent years, we have seen a clear shift toward biostimulating treatments in cosmetic medicine. Instead of simply adding volume with fillers, these biostimulating treatments focus on restoring and strengthening the skin’s structure itself.
At JECT Clinics, we are strong advocates of this development. We believe that the most beautiful results are achieved when treatments support and enhance the skin’s natural processes. Polynucleotides such as Rejuran fit perfectly within this vision: a treatment that helps the skin repair itself from the inside out, resulting in a healthy, fresh, and natural appearance.
Interested in a Rejuran treatment? Book your appointment now with one of our specialized cosmetic doctors.